Unable to boot up anymore

My up squared just unable to boot up any more after 1 week...
I just use it as a normal PC in this week (with 7x24 )....
And it just not start any more with a Screaming (high frequenc sound, no more blue lights)
after inserting the power supply.
I am using the power supply you provide.
What should i do and how can i repair.

Thank a lot